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ADBR2 Gene interacts with Childhood Adversity – impacting Pre-disposition to vulnerability or resiliance

April 19, 2018 10:46 am : Brain Science
IMPORTANT RESEARCH  In 2014 researchers from Columbia University and Michigan University published their first evidence that a gene called “ADBR2” interacts with childhood adversity and either result in a vulnerability or resilience to developing PTSD symptoms following adult trauma. Your genotype is your complete heritable genetic identity. Individuals with two or more experiences (see your more »

Large Gene Expression Study Sheds Light on Causal Factors in Five Brain Disorders

April 6, 2018 3:08 pm : Brain Science
6-Apr-2018: By: Daniel Geschwind, M.D., Ph.D. Researchers studying gene expression in cerebral cortex tissue sampled from postmortem brains have identified patterns of shared and distinct gene expression patterns in autism, schizophrenia, bipolar disorder, depression and alcoholism. The results, published February 9 in Science, offer a unique glimpse at genome-wide, disorder-related molecular signatures that could help fine-tune more »

Substance Use Carries Mental Health Risks–Yes, Even Marijuana!

March 26, 2018 5:59 pm : Brain Science, Breaking News
Substance Use Carries Mental Health Risks—Yes, Even Marijuana By Dr. Elinore F. McCance-Katz | Mar. 26, 2018   Each year, SAMHSA holds Prevention Day as an opportunity to share best practices and data with professionals who work day in and day out to end the cycles of substance use disorder sweeping our country. It’s usually more »

Do you REALLY know your genetic predisposition?

January 15, 2018 1:57 pm : Best Practice, Brain Science
Do you really know your full multi-generational family history for addiction and/or mental health issues? Genetics plays a key role: upwards of 80% (for bi-polar and schizophrenia) and upwards of 60% for addictions. So, understanding our relative’s mental health and history of addictive behaviors can help us take steps to avoid triggers and build resilience.     When more »

Pathways to the Future

November 19, 2017 8:04 pm : Brain Science BBR Foundation’s special edition!   Keep talking about genetics in our community.  

Scientists identify brain chemical abnormalities in earliest stage of psychosis

October 17, 2017 9:56 am : Brain Science
Read full article in here “Our findings suggest that glycine abnormalities may play a role in the earliest phases of psychotic disorders,” said Dr. Öngür. The researchers also measured increased glutamate levels in patients, which lines up with strong support for elevated glutamate reported in other studies of first-episode psychosis. The elevations in glutamate more »

Largest study to-date finds no Evidence for a Connection of Childhood Trauma and Polygenic Risk for depression

October 17, 2017 9:49 am : Brain Science
Download PDF summary of the study here Scientists perform largest study to-date to answer the question: “Does Childhood Trauma Moderate Polygenetic Risk for Depression?” Conclusion:  To conclude, no overall evidence was found for interaction between PRS and CT. Previously found interaction effects (27, 28) were no longer significant when applying more powerful discovery results. This more »

Nearly 80% percent of schizophrenia risk is genetic

October 9, 2017 5:50 pm : Brain Science, Breaking News
Largest twin study to date pins nearly 80 percent of schizophrenia risk on heritability PsyPost In the largest study of twins in schizophrenia research to date, researchers at the University of Copenhagen, Denmark, estimate that as much as 79% of schizophrenia risk may be explained by genetic factors. The estimate indicates that genetics have a more »

Study Identifies Signaling Molecule Involved in Resilience to Stress

September 22, 2017 6:48 pm : Brain Science, Breaking News
BBR study  Researchers find brain signaling by lipid 2-AG is important in promoting resilience. The findings suggest that a drug boosting 2-AG levels is a potentially useful approach for those engaged in trying to find new ways to treat stress-related psychiatric disorders, the researchers said.

Perspectives on Genetics!

July 4, 2017 12:02 pm : Brain Science, Breaking News
White paper presented at NAMI Conference in more lay terms.  Excellent research.   For years we have been providing mental health outreach in our local El Dorado County encouraging everyone to do their family tree for both mental health and addiction of any kind.   Notice that Schizophrenia, BiPolar and Autism Spectrum Disorder are highest more »

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